N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

Base Information

Chemical Name:N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide
CAS No.:1207436-59-6
Molecular Formula:C₁₉H₁₄ClN₅O₃
Molecular Weight:395.805
Hs Code.:

Synonyms:N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

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Chemical Property of N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

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Technology Process of N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

There total 2 articles about N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1207441-78-8
N-(3-(6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

: 622-95-7
4-chlorobenzyl bromide

: 1207436-59-6
N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

Guidance literature:: With potassium carbonate; In acetonitrile; for 12h; Reflux;

Reference yield: 36.0%

: 1207441-62-0
(Z)-N-(4-chlorobenzyl)-2-cyano-2-(2-((3-aminophenyl)acetamide)hydrazono)acetamide

: 541-41-3
chloroformic acid ethyl ester

: 1207436-59-6
N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

Guidance literature:: In pyridine; at 120 ℃; for 6h;

Reference yield: 88.0%

: 1207436-59-6
N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide

: 1207441-81-3
4-(4-chlorobenzyl)-2-(3-aminophenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxylic acid

Guidance literature:: N-(3-(4-(4-chlorobenzyl)-6-cyano-3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)acetamide; With hydrogenchloride; water; for 3h; Reflux;

With sodium carbonate; In water;

With acetic acid; In water; pH=4;