2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide

Base Information

• Chemical Name: 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide
• CAS No.: 767268-92-8
• Molecular Formula: C₂₁H₂₅Cl₂N₃O
• Molecular Weight: 406.355
• Mol file: 767268-92-8.mol

Synonyms:2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide

Chemical Property of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide

There total 1 articles about 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-(3,4-Dichloro-phenyl)-N-methyl-N-[(R)-1-(3-nitro-phenyl)-2-pyrrolidin-1-yl-ethyl]-acetamide → 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide (767268-92-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; under 1551.4 Torr;

DOI:10.1016/S0960-894X(97)00406-X

Reference yield: 80.0%

fluoresceinyl 5-isothiocyanate (1173-43-9) + 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide (767268-92-8) → 5-{3-[3-((R)-1-{[2-(3,4-Dichloro-phenyl)-acetyl]-methyl-amino}-2-pyrrolidin-1-yl-ethyl)-phenyl]-thioureido}-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid

Guidance literature:

In tetrahydrofuran;

DOI:10.1016/S0960-894X(97)00406-X

Reference yield:

acetyl chloride (75-36-5) + 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R)-1-(3-aminophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide (767268-92-8) → N-[(R)-1-(3-Acetylamino-phenyl)-2-pyrrolidin-1-yl-ethyl]-2-(3,4-dichloro-phenyl)-N-methyl-acetamide

Guidance literature:

With triethylamine; In dichloromethane;

DOI:10.1016/S0960-894X(97)00406-X