Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide

Base Information

• Chemical Name: Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide
• CAS No.: 1235993-24-4
• Molecular Formula: C₂₃H₂₆N₄O₃
• Molecular Weight: 406.484
• Mol file: 1235993-24-4.mol

Synonyms:Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide

Chemical Property of Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide

There total 1 articles about Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

4-amino-N-cyclohexyl-N-ethyl-3-hydroxy-benzamide (1235993-22-2) + imidazo[1,2-a]pyridine-3-carboxylic acid (6200-60-8) → Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide (1235993-24-4)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield: 21.0%

Imidazo[1,2-a]pyridine-3-carboxylic acid [4-(cyclohexyl-ethyl-carbamoyl)-2-hydroxy-phenyl]-amide (1235993-24-4) → 2-Imidazo[1,2-a]pyridin-3-yl-benzooxazole-6-carboxylic acid cyclohexyl-ethyl-amide (1235993-26-6)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; Reflux;

upstream raw materials:

4-amino-N-cyclohexyl-N-ethyl-3-hydroxy-benzamide

imidazo[1,2-a]pyridine-3-carboxylic acid

Downstream raw materials:

2-Imidazo[1,2-a]pyridin-3-yl-benzooxazole-6-carboxylic acid cyclohexyl-ethyl-amide