Technology Process of 2-chloro-5-iodo-1,3-phenylene diacetate
There total 3 articles about 2-chloro-5-iodo-1,3-phenylene diacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N-chloro-succinimide; acetic acid / 3 h / 20 °C
2.1: sodium nitrite; sulfuric acid / water / 0.5 h / 0 °C
2.2: 0.5 h / 20 - 80 °C / Reflux
3.1: boron tribromide / dichloromethane / 0 - 20 °C
3.2: Cooling with ice bath
4.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
With
N-chloro-succinimide; sulfuric acid; boron tribromide; acetic acid; N-ethyl-N,N-diisopropylamine; sodium nitrite;
In
dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: boron tribromide / dichloromethane / 0 - 20 °C
1.2: Cooling with ice bath
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
With
boron tribromide; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium nitrite; sulfuric acid / water / 0.5 h / 0 °C
1.2: 0.5 h / 20 - 80 °C / Reflux
2.1: boron tribromide / dichloromethane / 0 - 20 °C
2.2: Cooling with ice bath
3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C
With
sulfuric acid; boron tribromide; N-ethyl-N,N-diisopropylamine; sodium nitrite;
In
dichloromethane; water;
