4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Base Information

Chemical Name:4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide
CAS No.:82099-07-8
Molecular Formula:C₂₃H₂₉N₃O₃S₂*HI
Molecular Weight:587.546
Hs Code.:

Synonyms:4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Suppliers and Price of 4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

There total 8 articles about 4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.5%

: 82098-86-0
4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzamide

: 74-88-4
methyl iodide

: 82099-07-8
4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Guidance literature:: In acetone; Ambient temperature;

Reference yield:

: 100-27-6
2-(4-nitrophenyl)ethanol

: 82099-07-8
4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Guidance literature:: Multi-step reaction with 8 steps

1: 70 percent / H₂ / Raney-nickel / methanol / Ambient temperature

2: 1.) NaNO₂/conc. HCl; 2.) CuCN/NaCN / 1.) H₂O, 0-5 deg C; 2.) benzene, 0-5 deg C, 30 min; room temp., 4 h

3: 63 percent / PBr₃ / CHCl₃ / 1.5 h / Heating

4: 1.) KI; 2.) Na / 1.) EtOH, reflux; 2.) EtOH, reflux, 5 h

6: 60 percent / benzene / Ambient temperature

7: 100 percent / H₂S (gas), TEA / pyridine / Ambient temperature

8: 75.5 percent / acetone / Ambient temperature

With hydrogenchloride; TEA; hydrogen sulfide; sodium cyanide; hydrogen; sodium; phosphorus tribromide; potassium iodide; sodium nitrite; nickel; In pyridine; methanol; chloroform; acetone; benzene;

Reference yield:

: 72054-56-9
4-(2-bromoethyl)benzonitrile

: 82099-07-8
4-[4-Oxo-4-pyrrolidin-1-yl-3-(toluene-4-sulfonylamino)-butyl]-thiobenzimidic acid methyl ester; hydriodide

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) KI; 2.) Na / 1.) EtOH, reflux; 2.) EtOH, reflux, 5 h

3: 60 percent / benzene / Ambient temperature

4: 100 percent / H₂S (gas), TEA / pyridine / Ambient temperature

5: 75.5 percent / acetone / Ambient temperature

With TEA; hydrogen sulfide; sodium; potassium iodide; In pyridine; acetone; benzene;