1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Base Information

Chemical Name:1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine
CAS No.:1630041-36-9
Molecular Formula:C₃₁H₃₃Cl₂N₃O₂
Molecular Weight:550.528
Hs Code.:

Synonyms:1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Suppliers and Price of 1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Chemical Property:

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Technology Process of 1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

There total 6 articles about 1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-89-4
piperidine

: 1630041-33-6
C₂₆H₂₃Cl₃N₂O₂

: 1630041-36-9
1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Guidance literature:: With triethylamine; In acetonitrile; at 20 ℃;
DOI:10.2174/1570180811666140116214111

Reference yield:

: 1630041-30-3
4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

: 1630041-36-9
1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride; water; ethanol / 12 h / Reflux

2: thionyl chloride / dichloromethane / 0.5 h / 0 °C

3: triethylamine / acetonitrile / 20 °C

With thionyl chloride; ethanol; water; sodium hydride; triethylamine; In dichloromethane; acetonitrile;
DOI:10.2174/1570180811666140116214111

Reference yield:

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 1630041-36-9
1-((4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazol-1-yl)methyl)piperidine

Guidance literature:: Multi-step reaction with 6 steps

1: potassium carbonate / acetone / 3 h / Reflux

2: potassium carbonate / acetone / 5 h / 40 °C

3: ammonium acetate; acetic acid / 1 h / Reflux

4: sodium hydride; water; ethanol / 12 h / Reflux

5: thionyl chloride / dichloromethane / 0.5 h / 0 °C

6: triethylamine / acetonitrile / 20 °C

With thionyl chloride; ethanol; ammonium acetate; water; sodium hydride; potassium carbonate; acetic acid; triethylamine; In dichloromethane; acetone; acetonitrile;
DOI:10.2174/1570180811666140116214111