4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

Base Information

Chemical Name:4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole
CAS No.:1630041-30-3
Molecular Formula:C₂₅H₂₂Cl₂N₂O₂
Molecular Weight:453.368
Hs Code.:

Synonyms:4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

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Chemical Property of 4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

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Technology Process of 4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

There total 3 articles about 4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 3457-46-3,88372-92-3
4,4'-dichlorobenzil

: 107811-48-3
2-isopropoxy-4-methoxybenzene-1-carboaldehyde

: 1630041-30-3
4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

Guidance literature:: With ammonium acetate; acetic acid; for 1h; Reflux;
DOI:10.2174/1570180811666140116214111

Reference yield:

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 1630041-30-3
4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 5 h / 40 °C

2: ammonium acetate; acetic acid / 1 h / Reflux

With ammonium acetate; potassium carbonate; acetic acid; In acetone;
DOI:10.2174/1570180811666140116214111

Reference yield:

: 95-01-2
2,4-Dihydroxybenzaldehyde

: 1630041-30-3
4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / acetone / 3 h / Reflux

2: potassium carbonate / acetone / 5 h / 40 °C

3: ammonium acetate; acetic acid / 1 h / Reflux

With ammonium acetate; potassium carbonate; acetic acid; In acetone;
DOI:10.2174/1570180811666140116214111