methyl (S)-<2-2H₁>-O-benzylglycolate

Base Information

• Chemical Name: methyl (S)-<2-2H₁>-O-benzylglycolate
• CAS No.: 89789-27-5
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 181.196
• Mol file: 89789-27-5.mol

Synonyms:methyl (S)-<2-2H₁>-O-benzylglycolate

Chemical Property of methyl (S)-<2-2H₁>-O-benzylglycolate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (S)-<2-2H₁>-O-benzylglycolate

There total 1 articles about methyl (S)-<2-2H₁>-O-benzylglycolate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

benzyl bromide (100-39-0) + methyl (S)-<2-2H1>glycolate → methyl (S)-<2-2H1>-O-benzylglycolate (89789-27-5)

Guidance literature:

With silver(l) oxide; In diethyl ether; at 42 ℃;

DOI:10.1021/ja00322a037

Reference yield:

methyl (S)-<2-2H1>-O-benzylglycolate (89789-27-5) → (S)-<2-2H1>-O-benzylglycolamide

Guidance literature:

With ammonia; In methanol; at 25 ℃; for 144h;

DOI:10.1021/ja00322a037

Reference yield:

methyl (S)-<2-2H1>-O-benzylglycolate (89789-27-5) → (S)-<1-2H1>-2-aminoethanol hydrochloride (89789-31-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.31 g / NH₃ (liq.) / methanol / 144 h / 25 °C

2: 41 percent / BH₃ / tetrahydrofuran / 12 h / Heating

With borane; ammonia; In tetrahydrofuran; methanol;

DOI:10.1021/ja00322a037

upstream raw materials:

benzyl bromide

Downstream raw materials:

(S)-<1-2H₁>-2-aminoethanol hydrochloride