Technology Process of N-((R,Ss,E)-2-ethoxy-1-p-tolylpenta-2,4-dienyl)-4-methylbenzenesulfinamide
There total 1 articles about N-((R,Ss,E)-2-ethoxy-1-p-tolylpenta-2,4-dienyl)-4-methylbenzenesulfinamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,1-diethoxy-but-2-ene;
With
n-butyllithium; potassium tert-butylate;
In
tetrahydrofuran; hexane;
at -78 - -40 ℃;
for 2h;
Inert atmosphere;
(S)-N-4-methylbenzylidene-4-methylbenzenesulfinamide;
In
tetrahydrofuran; hexane;
at -90 ℃;
diastereoselective reaction;
Inert atmosphere;
DOI:10.1021/jo1024943
- Guidance literature:
-
N-((R,Ss,E)-2-ethoxy-1-p-tolylpenta-2,4-dienyl)-4-methylbenzenesulfinamide;
With
trifluoroacetic acid;
In
methanol;
at 0 - 20 ℃;
for 1.16667h;
Inert atmosphere;
With
sodium hydroxide;
In
methanol; water;
Inert atmosphere;
DOI:10.1021/jo1024943
