Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester

Base Information

• Chemical Name: Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester
• CAS No.: 409367-02-8
• Molecular Formula: C₂₆H₃₁NO₄
• Molecular Weight: 421.536

Synonyms:Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester

Chemical Property of Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester

Chemical Property:

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Technology Process of Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester

There total 2 articles about Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-Phenethyl-4-phenyl-butyryl)-piperidine-1-carboxylic acid tert-butyl ester (409367-01-7) + Chloro-oxo-acetic acid (4732-69-8) → Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester (409367-02-8)

Guidance literature:

With triethylamine; trifluoroacetic acid; In dichloromethane;

Reference yield:

→ Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester (409367-02-8)

Guidance literature:

Reference yield:

Oxo-[2-(2-phenethyl-4-phenyl-butyryl)-piperidin-1-yl]-acetic acid methyl ester (409367-02-8) + tert-butylmagnesium chloride (677-22-5) → 2-({1-oxo-[2-{2'-phenyl}ethyl]-4-phenyl}-butyl)-1-(3,3-dimethyl-1,2-dioxobutyl)piperidine

Guidance literature:

With ammonium chloride; In tetrahydrofuran;

upstream raw materials:

2-(2-Phenethyl-4-phenyl-butyryl)-piperidine-1-carboxylic acid tert-butyl ester

Chloro-oxo-acetic acid

Downstream raw materials:

3,3-Dimethyl-1-[2-(2-phenethyl-4-phenyl-butyryl)-piperid in-1-yl]-pentane-1,2-dione

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