α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester

Base Information

• Chemical Name: α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester
• CAS No.: 300854-17-5
• Molecular Formula: C₂₇H₃₃NO₄
• Molecular Weight: 435.563

Synonyms:α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester

Chemical Property of α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester

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Technology Process of α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester

There total 1 articles about α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester (300854-17-5)

Guidance literature:

Reference yield:

α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester (300854-17-5) + 1-piperidin-4-yl-1-H-benzoimidazole → α-(R)-(3-(S)-((4-Benzoimidazol-1-yl-piperidin-1-yl)methyl)4-(S)-phenyl-pyrrolidin-1-yl)-cyclohexaneacetic acid, 4-methoxy-benzyl ester (301220-17-7)

Guidance literature:

With sodium tris(acetoxy)borohydride; silica gel; In tetrahydrofuran; methanol; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

α-(R)-(3-(R)-Formyl-4-(S)-phenyl-pyrrolidin-1-yl)cyclohexaneacetic acid, para-methoxybenzyl ester (300854-17-5) + 4-(benzothiazol-2-yl)-piperidine (51784-73-7) → α-(R)-(3-(S)-((4-(benzothiazol-2-yl)piperidin-1-yl)methyl)-4-(S)-phenylpyrrolidin-1-yl)-cyclohexaneacetic acid, 4-methoxybenzyl ester (301220-12-2)

Guidance literature:

With sodium tris(acetoxy)borohydride; silica gel; In tetrahydrofuran; hexane; ethyl acetate;

Downstream raw materials:

α-(R)-(3-(S)-((4-Benzoimidazol-1-yl-piperidin-1-yl)methyl)4-(S)-phenyl-pyrrolidin-1-yl)-cyclohexaneacetic acid, 4-methoxy-benzyl ester

(R)-Cyclohexyl-[(3S,4S)-3-(4-imidazo[4,5-b]pyridin-3-yl-piperidin-1-ylmethyl)-4-phenyl-pyrrolidin-1-yl]-acetic acid 4-methoxy-benzyl ester

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