5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene

Base Information

• Chemical Name: 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene
• CAS No.: 244177-19-3
• Molecular Formula: C₅₄H₆₈O₄
• Molecular Weight: 781.132
• Mol file: 244177-19-3.mol

Synonyms:5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene

Chemical Property of 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene

There total 1 articles about 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

25-benzyloxy-5,11,17,23-tetra-tert-butyl-26,27,28-trihydroxycalix[4]arene (135501-38-1,133744-83-9) + 1-iodo-propane (107-08-4) → 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene (244177-19-3)

Guidance literature:

With potassium carbonate; In acetonitrile; Heating;

DOI:10.1021/jo990336v

Reference yield: 71.0%

triethylene glycol di-(p-toluenesulfonate) (19249-03-7) + 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene (244177-19-3) → 5,11,17,23-Tetrakis(1,1-dimethylethyl)-25-benzyloxyα-26,28-(crown-4)α-27-hydroxyα-calix[4]arene (369600-26-0)

Guidance literature:

5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene; With sodium hydride; In tetrahydrofuran; for 4h; Heating;

triethylene glycol di-(p-toluenesulfonate); In tetrahydrofuran; for 20h; Further stages.; Heating;

DOI:10.1002/1521-3765(20010803)7:15<3354::AID-CHEM3354>3.0.CO;2-U

Reference yield: 70.0%

tetraethylene glycol di(p-toluenesulfonate) (37860-51-8) + 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-dihydroxy-calix[4]arene (244177-19-3) → 5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-crown-5-calix[4]arene, 1,3-alternate conformer (247247-65-0,247248-27-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 24h; Heating;

DOI:10.1021/jo990336v

upstream raw materials:

25-benzyloxy-5,11,17,23-tetra-tert-butyl-26,27,28-trihydroxycalix[4]arene

1-iodo-propane

Downstream raw materials:

5,11,17,23-tetrakis(1,1-dimethylethyl)-25-propoxy-27-benzyloxy-26,28-crown-5-calix[4]arene, 1,3-alternate conformer

5,11,17,23-Tetrakis(1,1-dimethylethyl)-25-benzyloxy^α-26,28-(crown-4)^α-27-hydroxy^α-calix[4]arene