methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate

Base Information

• Chemical Name: methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate
• CAS No.: 440644-08-6
• Molecular Formula: C₂₁H₂₄N₂O₆
• Molecular Weight: 400.431
• Mol file: 440644-08-6.mol

Synonyms:methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate

Chemical Property of methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate

There total 1 articles about methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-(Benzyloxycarbonyloxy)succinimide (13139-17-8) + methyl 3-amino-2-(aminomethyl)-propionate dihydrochloride (440644-06-4) → methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate (440644-08-6)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.1016/S0968-0896(01)00379-0

Reference yield:

N-methoxylamine hydrochloride (593-56-6) + methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate (440644-08-6) → N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionaldehyde O-methyloxime

Guidance literature:

methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate; With diisobutylaluminium hydride; In toluene; for 3h;

N-methoxylamine hydrochloride; In methanol; at 65 ℃; for 3.5h;

DOI:10.1016/S0968-0896(01)00379-0

Reference yield:

methyl N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionate (440644-08-6) → N,N'-(dibenzyloxycarbonyl)-3-amino-2-(aminomethyl)propionaldehyde

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; for 3h;

DOI:10.1016/S0968-0896(01)00379-0

upstream raw materials:

N-(Benzyloxycarbonyloxy)succinimide

methyl 3-amino-2-(aminomethyl)-propionate dihydrochloride