8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Base Information

Chemical Name:8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester
CAS No.:198124-47-9
Molecular Formula:C₄₁H₅₄O₈Si₂
Molecular Weight:731.046
Hs Code.:

8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Synonyms:8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Suppliers and Price of 8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

There total 8 articles about 8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 198124-74-2
8-Allyloxy-6-(tert-butyl-diphenyl-silanyloxy)-1,4-bis-methoxymethoxy-3,7-dimethyl-naphthalene-2-carboxylic acid

: 198124-47-9
8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 23 ℃; for 1h;
DOI:10.1139/cjc-79-11-1711

Reference yield:

: 198124-44-6
5-allyloxy-3-bromo-7-methoxymethoxy-2,6-dimethyl-[1,4]-naphthoquinone

: 198124-47-9
8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1.1: p-TsOH / methanol; CH₂Cl₂ / 6 h / Heating

2.1: 7.4 g / imidazole / dimethylformamide / 14 h

3.1: Adogen 464(R); Na₂S₂O₄ / CH₂Cl₂; H₂O / 0.5 h

3.2: NaOH / CH₂Cl₂; H₂O / 1 h / 23 °C

3.3: 82 percent / Hunig's base / CH₂Cl₂ / 4 h

4.1: 82 percent / n-BuLi / tetrahydrofuran / 0.33 h / -78 - 23 °C

5.1: 90 percent / PPh₃; DEAD / tetrahydrofuran / 1 h / 23 °C

With 1H-imidazole; n-butyllithium; sodium dithionite; Adogen 464(R); toluene-4-sulfonic acid; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; 5.1: Mitsunobu reaction;
DOI:10.1139/cjc-79-11-1711

Reference yield:

: 198124-45-7
5-allyloxy-3-bromo-7-(tert-butyldiphenylsilyloxy)-2,6-dimethyl-[1,4]-naphthoquinone

: 198124-47-9
8-allyloxy-6-(tert-butyldiphenylsilyloxy)-1,4-bis(methoxymethoxy)-3,7-dimethylnaphthalene-2-carboxylic acid β-trimethylsilylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: Adogen 464(R); Na₂S₂O₄ / CH₂Cl₂; H₂O / 0.5 h

1.2: NaOH / CH₂Cl₂; H₂O / 1 h / 23 °C

1.3: 82 percent / Hunig's base / CH₂Cl₂ / 4 h

2.1: 82 percent / n-BuLi / tetrahydrofuran / 0.33 h / -78 - 23 °C

3.1: 90 percent / PPh₃; DEAD / tetrahydrofuran / 1 h / 23 °C

With n-butyllithium; sodium dithionite; Adogen 464(R); triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; water; 3.1: Mitsunobu reaction;
DOI:10.1139/cjc-79-11-1711