<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Base Information

Chemical Name:<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane
CAS No.:159517-69-8
Molecular Formula:C₂₄H₃₀O₇
Molecular Weight:430.498
Hs Code.:

Synonyms:<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Suppliers and Price of <1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

There total 5 articles about <1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 100-39-0
benzyl bromide

: 159517-65-4
<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-hydroxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

: 159517-69-8
<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; 1.) 0 deg C, 5 min, 2.) r.t., 2 h;
DOI:10.7164/antibiotics.47.932

Reference yield:

: 100-39-0
benzyl bromide

: 159517-69-8
<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / NaH / dimethylformamide / 2 h / 0 °C

2: 91 percent / n-Bu₄NF / tetrahydrofuran / 1 h / 0 °C

3: 24 percent / Ti(O-i-Pr)4, L-DIPT, t-BuOOH / CH₂Cl₂; toluene / 22 h / Ambient temperature

4: 86 percent / NaH / dimethylformamide / 1.) 0 deg C, 5 min, 2.) r.t., 2 h

With titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate; tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.7164/antibiotics.47.932

Reference yield:

: 144901-13-3
<1S-(1α,4β,5α)>-2-<<(tert-Butyldimethylsilyl)oxy>methyl>-4,5-bis(methoxymethoxy)-2-cyclopenten-1-ol

: 159517-69-8
<1R-(1α,2β,3β,4α,5α)>-2-Benzyloxy-1-benzyloxymethyl-3,4-di(methoxymethoxy)-6-oxabicyclo<3.1.0>hexane

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / NaH / dimethylformamide / 2 h / 0 °C

2: 91 percent / n-Bu₄NF / tetrahydrofuran / 1 h / 0 °C

3: 24 percent / Ti(O-i-Pr)4, L-DIPT, t-BuOOH / CH₂Cl₂; toluene / 22 h / Ambient temperature

4: 86 percent / NaH / dimethylformamide / 1.) 0 deg C, 5 min, 2.) r.t., 2 h

With titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate; tetrabutyl ammonium fluoride; sodium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.7164/antibiotics.47.932