Technology Process of methyl 6-phenylaminoimidazo<1,2-a>pyridine-2-carbamate
There total 9 articles about methyl 6-phenylaminoimidazo<1,2-a>pyridine-2-carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 9 steps
1: PCl5 / steam bath
2: 49 percent / Na / ethanol; dioxane / 0.5 h / 30 - 35 °C
3: 75 percent / 1 h / 270 °C
4: 34 percent / SeO2 / dioxane; H2O / 18 h / Heating
5: 97 percent / SOCl2, dimethylformamide / benzene / 1 h / Heating
6: 90 percent / NaN3 / acetone; H2O / 0.5 h
7: aq. acetic acid / 0.33 h / 85 - 90 °C
8: hexamethylphosphoric acid triamide / 2 h / 100 °C
9: 86 percent / sodium methoxide / methanol / 1 h / Heating
With
selenium(IV) oxide; thionyl chloride; sodium azide; phosphorus pentachloride; sodium methylate; sodium; N,N-dimethyl-formamide;
In
1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; ethanol; water; acetic acid; acetone; benzene;
DOI:10.1002/jhet.5570180402
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 34 percent / SeO2 / dioxane; H2O / 18 h / Heating
2: 97 percent / SOCl2, dimethylformamide / benzene / 1 h / Heating
3: 90 percent / NaN3 / acetone; H2O / 0.5 h
4: aq. acetic acid / 0.33 h / 85 - 90 °C
5: hexamethylphosphoric acid triamide / 2 h / 100 °C
6: 86 percent / sodium methoxide / methanol / 1 h / Heating
With
selenium(IV) oxide; thionyl chloride; sodium azide; sodium methylate; N,N-dimethyl-formamide;
In
1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; water; acetic acid; acetone; benzene;
DOI:10.1002/jhet.5570180402
