1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

Base Information

Chemical Name:1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt
CAS No.:178371-32-9
Molecular Formula:C₄₅H₅₀N₄O₉*ClH
Molecular Weight:827.374
Hs Code.:

1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

Synonyms:1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

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Chemical Property of 1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

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Technology Process of 1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

There total 7 articles about 1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(3,4,5-Trimethoxy-benzoyl)-3-[2-[4-[1-(4-carbomethoxy-phenylmethyl)-1H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine

: 178371-32-9
1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; diethyl ether; water;

Reference yield:

: lithium hydroxide monohydrate

: 1-(3,4,5-Trimethoxy-benzoyl)-3-[2-[4-[1-(4-carbomethoxy-phenylmethyl)-1H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine

: 178371-32-9
1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; diethyl ether; water;

Reference yield:

: 167262-72-8
1-(3,4,5-trimethoxy-benzoyl)-3-(3,4-dimethoxy-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine

: 178371-32-9
1-(3,4,5-trimethoxy-benzoyl)-3-[2-[4-[1-(4-carboxy-phenylmethyl)-1 H-benzoimidazole-2-carbonyl]-piperidin-1-yl]-ethyl]-3-(3,4-dimethoxy-phenyl)-pyrrolidine hydrochloride salt

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride; sodium hydrogencarbonate; trimethylamine / dichloromethane

4: hydrogenchloride / tetrahydrofuran; diethyl ether; water

With hydrogenchloride; sodium hydrogencarbonate; trimethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water;