Technology Process of N-carbomethoxy-N-methoxy-(2-chloromethyl)-aniline
There total 5 articles about N-carbomethoxy-N-methoxy-(2-chloromethyl)-aniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
isobutyl chloroformate;
In
acetonitrile;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: dichloromethane; chlorobenzene / 20 °C
1.2: 0 °C
2.1: hydrogen; 4-methyl-morpholine / platinum on carbon / 4 h / Inert atmosphere
3.1: sodium hydrogencarbonate / dichloromethane; water / 1.5 h / 0 °C
4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C
4.2: 20 °C
5.1: isobutyl chloroformate / acetonitrile / 20 °C
With
4-methyl-morpholine; hydrogen; sodium hydride; sodium hydrogencarbonate; isobutyl chloroformate;
platinum on carbon;
In
tetrahydrofuran; dichloromethane; water; chlorobenzene; acetonitrile; mineral oil;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: hydrogen; 4-methyl-morpholine / platinum on carbon / 4 h / Inert atmosphere
2.1: sodium hydrogencarbonate / dichloromethane; water / 1.5 h / 0 °C
3.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C
3.2: 20 °C
4.1: isobutyl chloroformate / acetonitrile / 20 °C
With
4-methyl-morpholine; hydrogen; sodium hydride; sodium hydrogencarbonate; isobutyl chloroformate;
platinum on carbon;
In
tetrahydrofuran; dichloromethane; water; acetonitrile; mineral oil;
