trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate

Base Information

• Chemical Name: trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate
• CAS No.: 89964-56-7
• Molecular Formula: C₁₆H₂₄O₄S
• Molecular Weight: 312.43
• Mol file: 89964-56-7.mol

Synonyms:trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate

Chemical Property of trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate

There total 2 articles about trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

trans-2-(1-hydroxy-1-methylethyl)cyclohexanol (24337-53-9,26343-52-2,26343-53-3,114128-90-4) + p-toluenesulfonyl chloride (98-59-9) → trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate (89964-56-7)

Guidance literature:

for 48h; Ambient temperature;

Reference yield:

methyl 2-hydroxycyclohexanecarboxylate (2236-11-5) → trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate (89964-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 29 percent / diethyl ether / 14 h / Heating

2: 82 percent / 48 h / Ambient temperature

In diethyl ether;

Reference yield: 77.0%

trans-2-(1-hydroxy-1-methylethyl)cyclohexyl p-toluenesulfonate (89964-56-7) → 1-(1-hydroxy-1-methylethyl)cyclohexene (25910-97-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 16h; Heating;

upstream raw materials:

trans-2-(1-hydroxy-1-methylethyl)cyclohexanol

p-toluenesulfonyl chloride

methyl 2-hydroxycyclohexanecarboxylate

Downstream raw materials:

1-(1-hydroxy-1-methylethyl)cyclohexene