1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate

Base Information

Chemical Name:1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate
CAS No.:1254170-97-2
Molecular Formula:C₂₂H₂₀BrClFN₃O₄
Molecular Weight:524.774
Hs Code.:

Synonyms:1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate

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Chemical Property of 1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate

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Technology Process of 1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate

There total 1 articles about 1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1254170-77-8
2-bromo-5-[2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl]pyridine

: 541-41-3
chloroformic acid ethyl ester

: 1254170-97-2
1-tert-butyl 5-ethyl 4-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,5-dicarboxylate

: 1254170-98-3
1-tert-butyl 4-ethyl 5-(6-bromopyridin-3-yl)-2-(2-chloro-6-fluorophenyl)-1H-imidazole-1,4-dicarboxylate

Guidance literature:: di-tert-butyl dicarbonate; 2-bromo-5-[2-(2-chloro-6-fluorophenyl)-1H-imidazol-4-yl]pyridine; With potassium carbonate; In tetrahydrofuran; for 12h; Reflux;

With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1.16667h;

chloroformic acid ethyl ester; In tetrahydrofuran; at -78 ℃; for 8.16667h;