2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate

Base Information

• Chemical Name: 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate
• CAS No.: 339276-10-7
• Molecular Formula: C₂₀H₂₂F₃NO₈
• Molecular Weight: 461.392
• Mol file: 339276-10-7.mol

Synonyms:2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate

Chemical Property of 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate

There total 1 articles about 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,3,4-tri-O-acetyl-L-rhamnopyranose (28915-80-2,40591-53-5,40591-54-6,40591-55-7,120449-19-6,120449-20-9,143332-42-7,148081-39-4,151413-57-9,151413-58-0) + 2,2,2-trifluoro-N-phenyl-acetimidoyl chloride (61881-19-4) → 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate (339276-10-7)

Guidance literature:

With potassium carbonate; In dichloromethane; at 25 ℃; for 3h;

DOI:10.1016/S0040-4039(01)00157-5

Reference yield: 88.0%

5-O-acetyl-3,4-di-O-benzyl-1-O-tert-butyldimethylsilyl-L-arabitol (853734-13-1) + 2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate (339276-10-7) → 5-O-acetyl-2-[O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)]-3,4-di-O-benzyl-1-O-tert-butyldimethylsilyl-L-arabitol (853734-14-2)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/ol050324y

Reference yield: 72.0%

2,3,4-tri-O-acetyl-L-rhamnopyranosyl (N-phenyl)-2,2,2-trifluoroacetimidate (339276-10-7) + 4',8-dihexanoyloxyisoflavone (602329-48-6) → 4',8-dihexanoyloxyisoflavone 7-O-2'',3'',4''-tri-O-acetyl-α-L-rhamnopyranoside (602329-57-7)

Guidance literature:

With 4 A molecular sieve; boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃;

DOI:10.1021/jo034553e

upstream raw materials:

2,3,4-tri-O-acetyl-L-rhamnopyranose

2,2,2-trifluoro-N-phenyl-acetimidoyl chloride

Downstream raw materials:

4',8-dihexanoyloxyisoflavone 7-O-2'',3'',4''-tri-O-acetyl-α-L-rhamnopyranoside

5-O-acetyl-2-[O-(2,3,4-tri-O-acetyl-α-L-rhamnopyranosyl)]-3,4-di-O-benzyl-1-O-tert-butyldimethylsilyl-L-arabitol