(-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate

Base Information

• Chemical Name: (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate
• CAS No.: 81115-72-2
• Molecular Formula: C₁₇H₂₂O₃
• Molecular Weight: 274.36
• Mol file: 81115-72-2.mol

Synonyms:(-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate

Chemical Property of (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate

There total 3 articles about (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

2-Phenylpropanal (34713-70-7) → (R)-2-phenylpropanal (93-53-8) + (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate (81115-72-2) + (S)-(-)-2-phenylpropyl (R)-(-)-2-phenylpropanoate (81115-66-4)

Guidance literature:

With 2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde; aluminium menthyloxide; In dichloromethane; at -78 ℃; for 24h;

DOI:10.1039/P19810003034

Reference yield:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde (1920-21-4) + 2-Phenylpropanal (34713-70-7) → (R)-2-phenylpropanal (93-53-8) + (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate (81115-72-2) + (S)-(-)-2-phenylpropyl (R)-(-)-2-phenylpropanoate (81115-66-4)

Guidance literature:

With aluminium menthyloxide; Yield given. Multistep reaction. Yields of byproduct given; 1) CH₂Cl₂, -78 deg C, 24 h;;

DOI:10.1039/P19810003034

Reference yield:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde (1920-21-4) → (-)-2-phenylpropyl 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate (81115-72-2) + (-)-3,4-dihydro-2,2,5-trimethyl-2H-pyran 3,4-dihydro-2,5-dimethyl-2H-pyran-2-carboxylate (81115-73-3)

Guidance literature:

With aluminium menthyloxide; 2-Phenylpropanal; In dichloromethane; at -78 ℃; for 24h;

DOI:10.1039/P19810003034

upstream raw materials:

2,5-dimethyl-3,4-dihydro-2H-pyran-2-carbaldehyde

2-Phenylpropanal