1-AMINOCYCLODODECANECARBOXYLIC ACID

Base Information

• Chemical Name: 1-AMINOCYCLODODECANECARBOXYLIC ACID
• CAS No.: 950-29-8
• Molecular Formula: C₁₃H₂₅NO₂
• Molecular Weight: 227.347
• Hs Code.: 2922499990
• Mol file: 950-29-8.mol

Synonyms:1-AMINOCYCLODODECANECARBOXYLIC ACID

Chemical Property of 1-AMINOCYCLODODECANECARBOXYLIC ACID

Chemical Property:

• PSA: 63.32000
• LogP: 3.77350

Purity/Quality:

97% ^*data from raw suppliers

1-AMINOCYCLODODECANE-1-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-AMINOCYCLODODECANECARBOXYLIC ACID

There total 3 articles about 1-AMINOCYCLODODECANECARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.27%

1,2-diazaspiro[4.11]hexadecane-2,4-dione (839-32-7) → 1-aminocyclododecanecarboxylic acid (950-29-8)

Guidance literature:

With sodium hydroxide; at 195 ℃; for 2.5h;

DOI:10.1016/j.ejmech.2007.08.010

Reference yield:

cyclododecanone (830-13-7) → 1-aminocyclododecanecarboxylic acid (950-29-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium carbonate / aq. ethanol / 55 - 60 °C

2: aq. NaOH / 72 h / Heating

With ammonium carbonate; sodium hydroxide; In ethanol;

DOI:10.1021/ja962905b

Reference yield:

→ 1-aminocyclododecanecarboxylic acid (950-29-8)

Guidance literature:

upstream raw materials:

1,2-diazaspiro[4.11]hexadecane-2,4-dione

cyclododecanone

Refernces

• 1、 Naydenova, Emilia D.,Todorov, Petar T.,Topashka-Ancheva, Margarita N.,Momekov, Georgi Ts.,Yordanova, Tsvetelina Z.,Konstantinov, Spiro M.,Troev, Kolio D.. "Novel N-(phosphonomethyl) glycine derivatives: Design, characterization and biological activity". . p. 1199 - 1205. Retrieved 2008/09/20.