(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Base Information

Chemical Name:(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid
CAS No.:1024829-72-8
Molecular Formula:C₂₉H₃₉N₃O₆
Molecular Weight:525.645
Hs Code.:

Synonyms:(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Suppliers and Price of (R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of (R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

There total 6 articles about (R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1024829-70-6
C₃₆H₄₅N₃O₆

: 1024829-72-8
(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Guidance literature:: C₃₆H₄₅N₃O₆; With hydrogen; palladium on activated charcoal; In methanol;

With hydrogenchloride; In water; acetone;

Reference yield: 96.3%

: methyl (R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvalerate

: 1024829-72-8
(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Guidance literature:: With lithium hydroxide monohydrate; In methanol; water; at 0 - 20 ℃; for 4h;

Reference yield:

: 18942-49-9
Boc-D-Phe-OH

: 1024829-72-8
(R)-2-((R)-2-((R)-2-tert-butyloxycarbonylamino-3-phenylpropanamido)-3-phenylpropanamido)-4-methylvaleric acid

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine; copper(II) choride dihydrate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: lithium hydroxide monohydrate; water / tetrahydrofuran / 2 h / 0 °C

3: N-ethyl-N,N-diisopropylamine; copper(II) choride dihydrate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / tetrahydrofuran / 0 °C / Inert atmosphere

4: lithium hydroxide monohydrate; water / tetrahydrofuran / 1.5 h / 0 °C

With copper(II) choride dihydrate; lithium hydroxide monohydrate; water; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran;