(3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol

Base Information

• Chemical Name: (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
• CAS No.: 157555-88-9
• Molecular Formula: C₁₄H₁₈O₄S
• Molecular Weight: 282.361

Synonyms:(3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol

Chemical Property of (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol

There total 7 articles about (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-O-benzyl-5-chloro-1,2-O-isopropylidene-5-S-phenyl-5-thio-α-D-xylofuranose → (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol (157555-88-9)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at -23 ℃; for 0.25h;

Reference yield: 64.0%

diphenyldisulfane (882-33-7) + 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose (6893-65-8,20513-95-5,20513-96-6,34981-06-1,40429-51-4,110349-61-6) → (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol (157555-88-9)

Guidance literature:

diphenyldisulfane; With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at 20 ℃; for 0.166667h; Inert atmosphere;

1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose; In tetrahydrofuran; ethanol; for 24h; Reflux;

DOI:10.1016/j.tet.2010.03.033

Reference yield:

thiophenol (108-98-5) + 1,2-O-isopropylidene-5-O-trifluoromethanesulfanyl-α-D-(-)-xylofuranose → (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol (157555-88-9)

Guidance literature:

thiophenol; With sodium hydride; In tetrahydrofuran; for 0.0333333h;

1,2-O-isopropylidene-5-O-trifluoromethanesulfanyl-α-D-(-)-xylofuranose; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/c1cc13300d

upstream raw materials:

thiophenol

3-O-benzoyl-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-α-D-xylofuranose

3-O-benzyl-1,2-O-isopropylidene-5-S-phenyl-5-thio-α-D-xylofuranose

diphenyldisulfane

Downstream raw materials:

C₄₂H₅₇O₆PS

C₂₆H₂₅O₆PS

1,2-O-isopropylidene-3-diphenylphosphinite-5-phenylsulfanyl-D-xylofuranose

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 157555-88-9 (3aR,5S,6R,6aR)-2,2-dimethyl-5-(phenylthiomethyl)-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol

Send

Send

Metric Ton KG G Pound L ML

Send

Send