2,6-Dichloro-4-methoxybenzoyl chloride

Base Information

Chemical Name:2,6-Dichloro-4-methoxybenzoyl chloride
CAS No.:127817-86-1
Molecular Formula:C₈H₅Cl₃O₂
Molecular Weight:239.485
Hs Code.:
DSSTox Substance ID:DTXSID801284485

Synonyms:2,6-Dichloro-4-methoxybenzoyl chloride;SCHEMBL11816616;DTXSID801284485;127817-86-1

Suppliers and Price of 2,6-Dichloro-4-methoxybenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,6-Dichloro-4-methoxybenzoyl chloride

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.935512
Heavy Atom Count:13
Complexity:186

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C(=C1)Cl)C(=O)Cl)Cl

Technology Process of 2,6-Dichloro-4-methoxybenzoyl chloride

There total 3 articles about 2,6-Dichloro-4-methoxybenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 94278-69-0
2,6-dichloro-4-methoxybenzoic acid

: 127817-86-1
2,6-Dichlor-4-methoxybenzoesaurechlorid

Guidance literature:: With thionyl chloride; Heating;
DOI:10.1002/ardp.19903230204

Reference yield:

: 86111-47-9
(2,6-dichloro-4-methoxy-phenyl)-methanol

: 127817-86-1
2,6-Dichlor-4-methoxybenzoesaurechlorid

Guidance literature:: Multi-step reaction with 2 steps

1: 54 percent / Tetrabutylammoniumpermanganat / pyridine / 1 h / 100 °C

2: 91 percent / SOCl₂ / Heating

With thionyl chloride; tetra-n-butylammonium permanganate; In pyridine;
DOI:10.1002/ardp.19903230204

Reference yield:

: 33719-74-3
3,5-dichloroanisole

: 127817-86-1
2,6-Dichlor-4-methoxybenzoesaurechlorid

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran; hexane / 1.5 h / -78 °C / Inert atmosphere

1.3: 0 °C

2.1: thionyl chloride / Reflux; Inert atmosphere

With n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane;
DOI:10.1021/jm400266t