4-NITROBENZENESULFENYL CHLORIDE

Base Information

• Chemical Name: 4-NITROBENZENESULFENYL CHLORIDE
• CAS No.: 937-32-6
• Molecular Formula: C6H4 Cl N O2 S
• Molecular Weight: 189.622
• Hs Code.: 2930909090
• Mol file: 937-32-6.mol

Synonyms:Benzenesulfenylchloride, 4-nitro- (9CI); Benzenesulfenyl chloride, p-nitro- (6CI,7CI,8CI);4-Nitrobenzenesulfenyl chloride; 4-Nitrophenylsulfenyl chloride;p-Nitrobenzenesulfenyl chloride; p-Nitrophenylsulfenyl chloride

Chemical Property of 4-NITROBENZENESULFENYL CHLORIDE

Chemical Property:

• Vapor Pressure: 1.37E-05mmHg at 25°C
• Melting Point: 48-51 °C(lit.)
• Refractive Index: 1.633
• Boiling Point: 125 °C0.1 mm Hg(lit.)
• Flash Point: >230 °F
• PSA: 71.12000
• Density: 1.48g/cm³
• LogP: 3.36390
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Nitrobenzenesulfenyl chloride technical grade, 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-NITROBENZENESULFENYL CHLORIDE

There total 12 articles about 4-NITROBENZENESULFENYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

para-nitrobenzenethiol (1849-36-1) → 4-nitrobenzenesulfenyl chloride (937-32-6)

Guidance literature:

With chlorine; In tetrachloromethane; at -20 - 20 ℃; for 3.5h;

DOI:10.1055/s-2004-829115

Reference yield: 96.0%

di(p-nitrophenyl) disulfide (100-32-3) → 4-nitrobenzenesulfenyl chloride (937-32-6)

Guidance literature:

With chlorine; In tetrachloromethane; at 60 ℃; for 3h;

DOI:10.1021/ja00532a042

Reference yield: 92.0%

di(p-nitrophenyl) disulfide (100-32-3) + N-chlorobenzamide (1821-34-7) → 4-nitrobenzenesulfenyl chloride (937-32-6) + N-benzoyl p-nitrobenzenesulfenamide (60199-37-3)

Guidance literature:

With tetrabutyl-ammonium chloride; In benzene; 1.) reflux, 15 min, 2.) 20 deg C, 4 h;

upstream raw materials:

di(p-nitrophenyl) disulfide

para-nitrobenzenethiol

C₁₀H₁₃ClN₂O₂S

1-acetylsulfanyl-4-nitro-benzene

Downstream raw materials:

N-Acetyl-p-nitrobenzenesulfenamide

di(p-nitrophenyl) disulfide

p-nitrophenyl p-nitrobenzenethiosulfonate

Dithiophosphorsaeure-O,O-diethyl-S-(4-nitrophenyl)-ester

Refernces

• 1、 Cheng, Yu-Fei,Gao, Wen-Chao,Niu, Yulan,Shang, Yu-Zhu,Tian, Jun,Yu, Xinzhang. "Synthesis of 4-chalcogenyl pyrazoles via electrophilic chalcogenation/cyclization of α,β-alkynic hydrazones". . p. 1806 - 1811. Retrieved 2020/03/17.
• 2、 Lei, Xiaofang,Wang, Yuanyuan,Fan, Erkang,Sun, Zhihua. "In Situ Activation of Disulfides for Multicomponent Reactions with Isocyanides and a Broad Range of Nucleophiles". supporting information. p. 1484 - 1487. Retrieved 2019/02/26.