(S)-Ethyl 1-methylpyrrolidine-2-carboxylate

Base Information

Chemical Name:(S)-Ethyl 1-methylpyrrolidine-2-carboxylate
CAS No.:936-14-1
Molecular Formula:C₈H₁₅NO₂
Molecular Weight:157.213
Hs Code.:
Mol file:936-14-1.mol

Synonyms:(S)-Ethyl 1-methylpyrrolidine-2-carboxylate;L-Proline, 1-methyl-, ethyl ester;30727-23-2;936-14-1;ethyl N-methyl-l-prolinate;SCHEMBL11490824

Suppliers and Price of (S)-Ethyl 1-methylpyrrolidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-Ethyl 1-methylpyrrolidine-2-carboxylate

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:157.110278721
Heavy Atom Count:11
Complexity:147

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1CCCN1C
Isomeric SMILES:CCOC(=O)[C@@H]1CCCN1C

Technology Process of (S)-Ethyl 1-methylpyrrolidine-2-carboxylate

There total 12 articles about (S)-Ethyl 1-methylpyrrolidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 64-17-5
ethanol

: 475-11-6,58123-62-9,68078-09-1
N-methyl-L-proline

: 42002-99-3,936-14-1
N-methyl-L-proline ethyl ester

Guidance literature:: With thionyl chloride; at 0 ℃; for 3.5h; Reflux;
DOI:10.1007/s00210-020-01868-4

Reference yield: 75.0%

: 172223-88-0
C₂₀H₂₆NO₄P

: 30727-23-2,42002-99-3,936-14-1
1-methyl-DL-prolin-ethyl ester

Guidance literature:: With lithium diisopropyl amide;
DOI:10.1016/0040-4039(95)01567-2

Reference yield: 43.0%

: 64-17-5
ethanol

: 475-11-6,58123-62-9,68078-09-1
N-methyl-D-proline

: 42002-99-3,936-14-1
N-methyl-D-proline ethyl ester

Guidance literature:: ethanol; N-methyl-D-proline; With thionyl chloride; for 12h; Reflux; Green chemistry;

With sodium carbonate; Green chemistry;
DOI:10.1039/c6gc00415f