(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Base Information

Chemical Name:(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate
CAS No.:1308338-97-7
Molecular Formula:C₂₁H₁₈F₅NO₄
Molecular Weight:443.37
Hs Code.:

Synonyms:(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Suppliers and Price of (S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

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Chemical Property of (S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Chemical Property:

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Technology Process of (S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

There total 3 articles about (S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 115962-35-1,144069-68-1,78879-20-6
(3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid

: 1308338-97-7
(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Guidance literature:: With dmap; diisopropyl-carbodiimide; In dichloromethane; at 0 - 20 ℃;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1308338-97-7
(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water

2: dmap; diisopropyl-carbodiimide / dichloromethane / 0 - 20 °C

With dmap; sodium hydrogencarbonate; diisopropyl-carbodiimide; In 1,4-dioxane; dichloromethane; water;

Reference yield:

: 74163-81-8
L-Tic-OH

: 1308338-97-7
(S)-2-tert-butyl 3-perfluorophenyl 3,4-dihydroisoquinoline-2,3(1H)-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water

2: dmap; diisopropyl-carbodiimide / dichloromethane / 0 - 20 °C

With dmap; sodium hydrogencarbonate; diisopropyl-carbodiimide; In 1,4-dioxane; dichloromethane; water;