4-Bromo-3-methyl-isothiazole

Base Information

• Chemical Name: 4-Bromo-3-methyl-isothiazole
• CAS No.: 930-42-7
• Molecular Formula: C4H4BrNS
• Molecular Weight: 178.052
• Hs Code.: 2934999090
• Mol file: 930-42-7.mol

Synonyms:4-Bromo-3-methylisothiazole;Isothiazole,4-bromo-3-methyl-;

Chemical Property of 4-Bromo-3-methyl-isothiazole

Chemical Property:

• Boiling Point: 106.058 °C at 760 mmHg
• Flash Point: 17.944 °C
• PSA: 41.13000
• Density: 1.702 g/cm³
• LogP: 2.21400
• Storage Temp.: 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-3-methylisothiazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Bromo-3-methyl-isothiazole

There total 4 articles about 4-Bromo-3-methyl-isothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methylisothiazole (693-92-5) → 4-bromo-3-methylisothiazole (930-42-7)

Guidance literature:

With bromine; In acetic acid; at 100 ℃;

DOI:10.1039/jr9630002032

Reference yield:

4-bromo-3-methyl-isothiazole-5-carboxylic acid (89284-01-5) → 4-bromo-3-methylisothiazole (930-42-7)

Guidance literature:

at 200 - 210 ℃;

DOI:10.1039/jr9630002032

Reference yield:

4-bromo-3-methyl-isothiazol-5-amine (85508-99-2) → 4-bromo-3-methylisothiazole (930-42-7)

Guidance literature:

Multistep reaction; (i) aq. NaNO₂, H₂SO₄, H₃PO₄, (ii) aq. H₃PO₂, Cu₂O;

DOI:10.1039/jr9630002032

upstream raw materials:

3-methylisothiazole

4-bromo-3-methyl-isothiazol-5-amine

4-bromo-3-methyl-isothiazole-5-carboxylic acid

Downstream raw materials:

4-bromo-5-(1,2-diphenyl-ethyl)-3-methyl-isothiazole

5-benzyl-4-bromo-3-methyl-isothiazole

5-(3-methyl-4-isothiazolyl)-2,4-bis(methyloxy)pyrimidine

4-bromo-3-dibromomethyl-isothiazole