2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal

Base Information

• Chemical Name: 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal
• CAS No.: 273936-77-9
• Molecular Formula: C₁₃H₂₁BrO₃
• Molecular Weight: 305.212
• Mol file: 273936-77-9.mol

Synonyms:2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal

Chemical Property of 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal

There total 3 articles about 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal → 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal (273936-77-9)

Guidance literature:

{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal; With dioxane dibromide;

With pyridine;

DOI:10.1016/S0040-4039(99)02172-3

Reference yield:

2-(3-methoxymethoxy-propyl)-cyclohexanone → 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal (273936-77-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: BuLi

2.1: 86 percent / DIBALH

3.1: Br₂-dioxane

3.2: pyridine

With n-butyllithium; dioxane dibromide; diisobutylaluminium hydride; 1.1: Horner-Emmons olefination / 2.1: Reduction / 3.1: Bromination / 3.2: Dehydrobromination;

DOI:10.1016/S0040-4039(99)02172-3

Reference yield:

{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanenitrile → 2-bromo-2-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}ethanal (273936-77-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 86 percent / DIBALH

2.1: Br₂-dioxane

2.2: pyridine

With dioxane dibromide; diisobutylaluminium hydride; 1.1: Reduction / 2.1: Bromination / 2.2: Dehydrobromination;

DOI:10.1016/S0040-4039(99)02172-3

Downstream raw materials:

3-{(2Z)-2-[(2E)-4-benzyloxy-1-bromo-2-butenylidene]cyclohexyl}-N-hydroxypropanamide

{[((2E,4Z)-4-bromo-4-{2-[3-(methoxymethyloxy)propyl]cyclohexylidene}-2-butenyl)oxy]methyl}benzene

3-{(2Z)-2-[(2E)-4-benzyloxy-1-bromo-2-butenylidene]cyclohexyl}propanoic acid

methyl 3-{(2Z)-2-[(2E)-4-benzyloxy-1-bromo-2-butenylidene]cyclohexyl}propanoate