2-CHLORO-N-(3-CHLORO-2-METHYLPHENYL)ACETAMIDE

Base Information

• Chemical Name: 2-CHLORO-N-(3-CHLORO-2-METHYLPHENYL)ACETAMIDE
• CAS No.: 99585-94-1
• Molecular Formula: C9H9 Cl2 N O
• Molecular Weight: 218.083
• Hs Code.: 2924299090
• Mol file: 99585-94-1.mol

Synonyms:o-Acetotoluidide,2,3'-dichloro- (6CI); 2-Chloro-N-(3-chloro-2-methylphenyl)acetamide; NSC 15942;NSC 37257

Chemical Property of 2-CHLORO-N-(3-CHLORO-2-METHYLPHENYL)ACETAMIDE

Chemical Property:

• Vapor Pressure: 4.31E-05mmHg at 25°C
• Refractive Index: 1.595
• Boiling Point: 350.7°C at 760 mmHg
• Flash Point: 165.9°C
• PSA: 29.10000
• Density: 1.345g/cm³
• LogP: 2.89870

Purity/Quality:

98%min ^*data from raw suppliers

2-Chloro-N-(3-chloro-2-methylphenyl)acetamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-N-(3-CHLORO-2-METHYLPHENYL)ACETAMIDE

There total 3 articles about 2-CHLORO-N-(3-CHLORO-2-METHYLPHENYL)ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-chloro-2-methylbenzenamine (87-60-5) → PCM-0102130 (99585-94-1)

Guidance literature:

Reference yield: 95.0%

→ PCM-0102130 (99585-94-1)

Guidance literature:

Reference yield: 77.6%

3-chloro-2-methylbenzenamine (87-60-5) + chloroacetyl chloride (79-04-9) → PCM-0102130 (99585-94-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 0.333333h;

DOI:10.1016/j.bioorg.2021.104979

upstream raw materials:

3-chloro-2-methylbenzenamine

chloroacetyl chloride

Refernces

• 1、 Hosseini, Samanesadat,Mahdavi, Mohammad,Pourmousavi, Seied Ali,Taslimi, Parham. "Synthesis, and in vitro biological evaluations of novel naphthoquinone conjugated to aryl triazole acetamide derivatives as potential anti-Alzheimer agents". . . Retrieved 2022/01/26.
• 2、 Sedaghati, Saeb,Azizian, Homa,Montazer, Mohammad Nazari,Mohammadi-Khanaposhtani, Maryam,Asadi, Mehdi,Moradkhani, Fatemeh,Ardestani, Mehdi Shafiee,Asgari, Mohammad Sadegh,Yahya-Meymandi, Azadeh,Biglar, Mahmood,Larijani, Bagher,Sadat-Ebrahimi, Seyed Esmaeil,Foroumadi, Alireza,Amanlou, Massoud,Mahdavi, Mohammad. "Novel (thio)barbituric-phenoxy-N-phenylacetamide derivatives as potent urease inhibitors: synthesis, in vitro urease inhibition, and in silico evaluations". . p. 37 - 48. Retrieved 2020/08/26.