(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Base Information

Chemical Name:(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester
CAS No.:116823-42-8
Molecular Formula:C₃₅H₄₉Cl₃N₆O₁₀S
Molecular Weight:852.233
Hs Code.:

(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Synonyms:(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Suppliers and Price of (S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

There total 12 articles about (S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 5978-22-3,1426213-63-9
N(ε)-benzoyloxycarbonyl-L-lysine tert-butyl ester hydrochloride

: 116823-41-7
(5S,6S,9R,14aS)-6-Methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carboxylic acid

: 116823-42-8
(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide; a) -70 deg C, 10 min, b) -15 deg C, 3 h, c) RT, overnight;
DOI:10.1246/bcsj.65.2227

Reference yield: 90.0%

: 116823-41-7
(5S,6S,9R)-6-Methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carboxylic acid

: 5978-22-3,1426213-63-9
N(ε)-benzoyloxycarbonyl-L-lysine tert-butyl ester hydrochloride

: 116823-42-8
(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide;
DOI:10.1016/S0040-4039(00)80212-9

Reference yield:

: 144822-77-5
(5S,6S,9R,14aS)-5-Amino-6-methyl-4,11,14-trioxo-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carboxylic acid

: 116823-42-8
(S)-6-Benzyloxycarbonylamino-2-{[(5S,6S,9R,14aS)-6-methyl-4,11,14-trioxo-5-(2,2,2-trichloro-ethoxycarbonylamino)-dodecahydro-7-thia-3a,10,13-triaza-cyclopentacyclotridecene-9-carbonyl]-amino}-hexanoic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / triethylamine (TEA) / dimethylformamide / 1 h / Ambient temperature

2: 90 percent / 1-hydroxybenzotriazole (HOBt), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) / dimethylformamide / a) -70 deg C, 10 min, b) -15 deg C, 3 h, c) RT, overnight

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In N,N-dimethyl-formamide;
DOI:10.1246/bcsj.65.2227