2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile

Base Information

• Chemical Name: 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile
• CAS No.: 93371-96-1
• Molecular Formula: C₁₈H₁₇NO₃S
• Molecular Weight: 327.404
• Mol file: 93371-96-1.mol

Synonyms:2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile

Chemical Property of 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile

There total 3 articles about 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-(4-amminofenil)propionico d'etile (32868-25-0) + 2-chlorosulfenylbenzoyl chloride (3950-02-5) → 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile (93371-96-1)

Guidance literature:

With pyridine; at 50 ℃; for 0.333333h;

Reference yield:

2,2'-dithiobenzoic acid (119-80-2) → 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile (93371-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) SOCl₂; 2.) Cl₂ / 1.) reflux; 2.) CCl₄

2: 50 percent / pyridine / 0.33 h / 50 °C

With pyridine; thionyl chloride; chlorine;

Reference yield:

2,2'-dithiodibenzoic acid dichloride (19602-82-5) → 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionato di etile (93371-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Cl₂ / CCl₄ / Ambient temperature

2: 45 percent / pyridine / 0.33 h / 50 °C

With chlorine; In pyridine; tetrachloromethane;

upstream raw materials:

2-(4-amminofenil)propionico d'etile

2-chlorosulfenylbenzoyl chloride

2,2'-dithiodibenzoic acid dichloride

2,2'-dithiobenzoic acid

Downstream raw materials:

acido 2-<4-(3-oxo-1,2-benzisotiazolin-2-il)fenil>propionico

Refernces

• 1、 Plazzi,Bordi,Vitali,et al.. "Synthesis and pain-killing activity of 4-(3-oxo-1,2-benzisothiazolin-2-yl)phenylalkanoic derivatives". . p. 788 - 796. Retrieved 2007/10/02.