(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Base Information

Chemical Name:(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester
CAS No.:158499-75-3
Molecular Formula:C₂₀H₂₈O₃S₂
Molecular Weight:380.573
Hs Code.:

Synonyms:(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Suppliers and Price of (5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

There total 7 articles about (5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 158499-74-2
(R)-(+)-3-(Benzyloxy)-3-(1,3-dithian-2-yl)-2,2-dimethylpropionaldehyd

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

: 158499-75-3
(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Guidance literature:: In dichloromethane; room t.;
DOI:10.1016/S0040-4039(99)00910-7

Reference yield:

: 277317-84-7
(2R/S,3R)-3-(Benzyloxy)tetrahydro-4,4-dimethylfuran-2-ol

: 158499-75-3
(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Guidance literature:: Multi-step reaction with 3 steps

1: molecular sieves 4 Angstroem; CF₃SO₃H / CH₂Cl₂ / 60 h / -10 - 20 °C

2: 89 percent / DMSO; NEt₃; pyridine*SO₃ / CH₂Cl₂ / 3.5 h / 0 - 20 °C

3: 65 percent / CH₂Cl₂ / 96 h / 20 °C

With trifluorormethanesulfonic acid; 4 A molecular sieve; sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine; In dichloromethane; 1: Ring cleavage / 2: Oxidation / 3: Condensation;
DOI:10.1039/a909549g

Reference yield:

: 20374-33-8
(R)-(+)-3-(Benzyloxy)-4,5-dihydro-4,4-dimethyl-furan-2(3H)-on

: 158499-75-3
(5R,2E)-(+)-5-(Benzyloxy)-5-(1,3-dithian-2-yl)-4,4-dimethylpent-2-ensaeure-ethylester

Guidance literature:: Multi-step reaction with 4 steps

1: 80 percent / DIBAL-H / CH₂Cl₂; toluene / 1 h / -78 °C

2: molecular sieves 4 Angstroem; CF₃SO₃H / CH₂Cl₂ / 60 h / -10 - 20 °C

3: 89 percent / DMSO; NEt₃; pyridine*SO₃ / CH₂Cl₂ / 3.5 h / 0 - 20 °C

4: 65 percent / CH₂Cl₂ / 96 h / 20 °C

With trifluorormethanesulfonic acid; 4 A molecular sieve; sulfur trioxide pyridine complex; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In dichloromethane; toluene; 1: Reduction / 2: Ring cleavage / 3: Oxidation / 4: Condensation;
DOI:10.1039/a909549g