(4R)-1-BOC-4-METHYL-D-PROLINE

Base Information

Chemical Name:(4R)-1-BOC-4-METHYL-D-PROLINE
CAS No.:871727-77-4
Molecular Formula:C₁₁H₁₉NO₄
Molecular Weight:229.276
Hs Code.:
Mol file:871727-77-4.mol

Synonyms:1,2-Pyrrolidinedicarboxylicacid,4-Methyl-,1-(1,1-diMethylethyl)ester,(2R,4R)-

Suppliers and Price of (4R)-1-BOC-4-METHYL-D-PROLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4r)-1-Boc-4-methyl-D-proline
10mg
$ 45.00

Synthonix
(2R,4R)-1-Boc-4-methylpyrrolidine-2-carboxylicacid 95+%
1g
$ 610.00

Matrix Scientific
(2R,4R)-1-Boc-4-methylpyrrolidine-2-carboxylicacid 95+%
1g
$ 2608.00

Chemenu
(2R,4R)-1-Boc-4-methylpyrrolidine-2-carboxylicacid 97%
5g
$ 1567.00

Chemenu
(2R,4R)-1-Boc-4-methylpyrrolidine-2-carboxylicacid 97%
1g
$ 448.00

AstaTech
(4R)-1-BOC-4-METHYL-D-PROLINE 97%
0.25 / G
$ 192.00

AstaTech
(4R)-1-BOC-4-METHYL-D-PROLINE 97%
5 / G
$ 1676.00

AstaTech
(4R)-1-BOC-4-METHYL-D-PROLINE 97%
1 / G
$ 479.00

American Custom Chemicals Corporation
(2R,4R)-4-METHYL-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 95.00%
1G
$ 1999.83

American Custom Chemicals Corporation
(2R,4R)-4-METHYL-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 95.00%
500MG
$ 1463.79

Total 22 raw suppliers

Chemical Property of (4R)-1-BOC-4-METHYL-D-PROLINE

Chemical Property:

Vapor Pressure:1.29E-05mmHg at 25°C
Refractive Index:1.49
Boiling Point:343.2°C at 760 mmHg
Flash Point:161.4°C
PSA：66.84000
Density:1.15g/cm³
LogP:1.65440
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(4r)-1-Boc-4-methyl-D-proline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (4R)-1-BOC-4-METHYL-D-PROLINE

There total 53 articles about (4R)-1-BOC-4-METHYL-D-PROLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 220047-75-6
tert-butyl (2S,4R)-2-(hydroxymethyl)-4-methylpyrrolidine-1-carboxylate

: 364750-80-1,871727-77-4
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-methylpyrrolidine-2-carboxylic acid

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In water; acetonitrile; at 20 ℃; for 15h;
DOI:10.3987/COM-18-S(F)8

Reference yield: 44.0%

: C₁₁H₁₉NO₄

: 364750-80-1,871727-77-4
(2S,4R)-1-[(tert-butoxy)carbonyl]-4-methylpyrrolidine-2-carboxylic acid

Guidance literature:: C₁₁H₁₉NO₄; With trimethylaluminum; N,O-dimethylhydroxylamine*hydrochloride; In tetrahydrofuran; toluene; at -30 - 23 ℃; for 0.666667h; Inert atmosphere;

With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at -78 - 23 ℃; for 1h; Further stages; Inert atmosphere;
DOI:10.1021/acs.joc.8b00248