3-Isopropoxyazetidine hydrochloride

Base Information

• Chemical Name: 3-Isopropoxyazetidine hydrochloride
• CAS No.: 871657-49-7
• Molecular Formula: C6H13 N O . Cl H
• Molecular Weight: 151.636
• Hs Code.: 2933990090
• European Community (EC) Number: 838-123-4
• DSSTox Substance ID: DTXSID90692892
• Mol file: 871657-49-7.mol

Synonyms:871657-49-7;3-ISOPROPOXYAZETIDINE HYDROCHLORIDE;3-Isopropoxy-Azetidine Hydrochloride;3-(propan-2-yloxy)azetidine hydrochloride;3-Isopropoxy-azetidine HCl;3-propan-2-yloxyazetidine;hydrochloride;MFCD06804558;3-isopropoxyazetidine-HCl;3-Isopropoxyazetidine HCl;SCHEMBL3244899;DTXSID90692892;QSKVFUMEPLXIRZ-UHFFFAOYSA-N;3-(1-Methylethoxy)-azetidine HCl;AKOS015950904;3-isopropoxyazacyclobutane hydrochloride;AB30393;GS-5711;3-ISOPROPOXYAZETIDINEHYDROCHLORIDE;SY035867;CS-0051664;A26675;EN300-128465;P10423;F2167-3596;3-[(Propan-2-yl)oxy]azetidine--hydrogen chloride (1/1)

Chemical Property of 3-Isopropoxyazetidine hydrochloride

Chemical Property:

• PSA: 21.26000
• LogP: 1.51400
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 151.0763918
• Heavy Atom Count: 9
• Complexity: 68.9

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-isopropoxyazetidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1CNC1.Cl

Technology Process of 3-Isopropoxyazetidine hydrochloride

There total 1 articles about 3-Isopropoxyazetidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-((propan-2-yl)oxy)azetidine hydrochloride (871657-49-7)

Guidance literature:

Reference yield: 98.0%

3-((propan-2-yl)oxy)azetidine hydrochloride (871657-49-7) + Bromodiphenylmethane (776-74-9) → 1-benzhydryl-3-isopropoxyazetidine

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 100 ℃; for 2h;

DOI:10.1021/jacs.0c05131

Reference yield: 87.0%

3-((propan-2-yl)oxy)azetidine hydrochloride (871657-49-7) + 4-(4-(aminomethyl)-3-methylphenyl)-N-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-amine hydrochloride + 1,1'-carbonyldiimidazole (530-62-1) → 3-((propan-2-yl)oxy)-N-(2-methyl-4-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)benzyl)azetidine-1-carboxamide trifluoroaceti acid

Guidance literature:

4-(4-(aminomethyl)-3-methylphenyl)-N-(1-methyl-1H-pyrazol-4-yl)pyrimidin-2-amine hydrochloride; 1,1'-carbonyldiimidazole; With triethylamine; In tetrahydrofuran; at 20 ℃; for 2h;

3-((propan-2-yl)oxy)azetidine hydrochloride; In tetrahydrofuran; at 20 ℃;

Refernces