17-Oxo-5,6-epoxyandrostan-3-yl acetate

Base Information

Chemical Name:17-Oxo-5,6-epoxyandrostan-3-yl acetate
CAS No.:14545-93-8
Molecular Formula:C₂₁H₃₀O₄
Molecular Weight:346.467
Hs Code.:
NSC Number:134931
DSSTox Substance ID:DTXSID30932608

Synonyms:14545-93-8;17-oxo-5,6-epoxyandrostan-3-yl acetate;NSC134931;DTXSID30932608;NSC-134931;9a,11b-dimethyl-9-oxohexadecahydrocyclopenta[1,2]phenanthro[8a,9-b]oxiren-3-yl acetate

Suppliers and Price of 17-Oxo-5,6-epoxyandrostan-3-yl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 17-Oxo-5,6-epoxyandrostan-3-yl acetate

Chemical Property:

Vapor Pressure:2.21E-08mmHg at 25°C
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:346.21440943
Heavy Atom Count:25
Complexity:644

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)OC1CCC2(C3CCC4(C(C3CC5C2(C1)O5)CCC4=O)C)C

Technology Process of 17-Oxo-5,6-epoxyandrostan-3-yl acetate

There total 11 articles about 17-Oxo-5,6-epoxyandrostan-3-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 50629-91-9,68974-65-2
Acetic acid (3S,5R,6R,10R,13S)-6-chloro-5-hydroxy-10,13-dimethyl-17-oxo-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester

: 6585-68-8,14545-93-8,68974-62-9
3β-Acetoxy-5α,6α-epoxy-5α-androstanon-(17)

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 12h; Inert atmosphere;

Reference yield: 39.3%

: 853-23-6
prasterone acetate

: 1449-61-2
3-O-acetyl-7-oxo-dehydroepiandrosterone

: 37976-94-6,517894-20-1
7α-hydroxy-17-oxoandrost-5-ene-3β-yl acetate

: 6585-68-8
3β-acetoxy-5β,6β-epoxyandrostan-17-one

: 14545-93-8
5α,6α-epoxy-17-oxoandrostan-3β-yl acetate

Guidance literature:: With ferric picolinate complexes; dihydrogen peroxide; In acetonitrile; for 3h; Ambient temperature;
DOI:10.1248/cpb.45.750

Reference yield:

: 853-23-6
prasterone acetate

: 1449-61-2
3-O-acetyl-7-oxo-dehydroepiandrosterone

: 6585-68-8
3β-acetoxy-5β,6β-epoxyandrostan-17-one

: 14545-93-8
5α,6α-epoxy-17-oxoandrostan-3β-yl acetate

Guidance literature:: With Mn(OTf)₂(^dMMpdp); dihydrogen peroxide; trimethylpyruvic acid; In water; ethyl acetate; acetonitrile; at 20 ℃; for 1h; Reagent/catalyst; diastereoselective reaction;
DOI:10.1021/ol403018x