1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid

Base Information

• Chemical Name: 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid
• CAS No.: 199330-51-3
• Molecular Formula: C₉H₁₇NO₂
• Molecular Weight: 171.239
• Mol file: 199330-51-3.mol

Synonyms:1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid

Chemical Property of 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid

There total 3 articles about 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,4-dimethylcyclohexenone (1073-13-8) → 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid (199330-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / (+)-limonene / Pd/C

2: ammonium carbonate / aq. ethanol / 55 - 60 °C

3: aq. NaOH / 72 h / Heating

With ammonium carbonate; sodium hydroxide; D-limonene; (+)-limonene; palladium on activated charcoal; In ethanol;

DOI:10.1021/ja962905b

Reference yield:

4,4-dimethylcyclohexane-1-one (4255-62-3) → 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid (199330-51-3)

Guidance literature:

Multi-step reaction with 2 steps

1: ammonium carbonate / aq. ethanol / 55 - 60 °C

2: aq. NaOH / 72 h / Heating

With ammonium carbonate; sodium hydroxide; In ethanol;

DOI:10.1021/ja962905b

Reference yield:

8,8-Dimethyl-1,3-diaza-spiro[4.5]decane-2,4-dione → 1-Amino-4,4-dimethyl-cyclohexanecarboxylic acid (199330-51-3)

Guidance literature:

With sodium hydroxide; for 72h; Heating;

DOI:10.1021/ja962905b

upstream raw materials:

4,4-dimethylcyclohexenone

4,4-dimethylcyclohexane-1-one

Downstream raw materials:

1-tert-Butoxycarbonylamino-4,4-dimethyl-cyclohexanecarboxylic acid

1-[(1-tert-Butoxycarbonylamino-4,4-dimethyl-cyclohexanecarbonyl)-amino]-4,4-dimethyl-cyclohexanecarboxylic acid methyl ester