3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt

Base Information

• Chemical Name: 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt
• CAS No.: 958850-97-0
• Molecular Formula: C₈H₁₁N*C₁₅H₁₂BrClO₂
• Molecular Weight: 460.798
• Mol file: 958850-97-0.mol

Synonyms:3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt

Chemical Property of 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt

There total 3 articles about 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3-bromophenyl)-3-(4-chlorophenyl)propionic acid (941280-51-9) + (S)-1-phenyl-ethylamine (2627-86-3) → 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt (958850-97-0)

Guidance literature:

In toluene; Industry scale;

Reference yield:

3-Bromophenylacetic acid (1878-67-7) → 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt (958850-97-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -28 - 0 °C

2: toluene

With lithium hexamethyldisilazane; In tetrahydrofuran; toluene;

Reference yield:

1-Chloro-4-(chloromethyl)benzene (104-83-6) → 3-(4-chlorophenyl)-2-(3-bromophenyl)propanoic acid, (S)-methylbenzylamine salt (958850-97-0)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / 2 h / -28 - 0 °C

2: toluene

With lithium hexamethyldisilazane; In tetrahydrofuran; toluene;

upstream raw materials:

2-(3-bromophenyl)-3-(4-chlorophenyl)propionic acid

(S)-1-phenyl-ethylamine

3-Bromophenylacetic acid

1-Chloro-4-(chloromethyl)benzene

Downstream raw materials:

C₁₅H₁₁BrCl₂O