trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97%

Base Information

• Chemical Name: trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97%
• CAS No.: 870717-91-2
• Molecular Formula: C₁₆H₂₃BO₂
• Molecular Weight: 258.168
• Hs Code.: 2934999090
• Mol file: 870717-91-2.mol

Synonyms:trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97%;E-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 2-(E-2-(4-Ethylphenyl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property of trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97%

Chemical Property:

• Vapor Pressure: 0.00123mmHg at 25°C
• Melting Point: 46-51 °C
• Refractive Index: 1.503
• Boiling Point: 308.5°C at 760 mmHg
• Flash Point: 110 °C
• PSA: 18.46000
• Density: 0.98g/cm³
• LogP: 3.89360
• Storage Temp.: 2-8°C

Purity/Quality:

95% ^*data from raw suppliers

trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97%

There total 3 articles about trans-2-(4-Ethylphenyl)vinylboronic acid pinacol ester, 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-ethyl-4-ethynylbenzene (40307-11-7) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → (E)-4,4,5,5-tetramethyl-2-(2-(4-ethylphenyl)ethenyl)-1,3,2-dioxaborolane (870717-91-2)

Guidance literature:

With tris(bis(trimethylsilyl)amido)lanthanum(III); In neat (no solvent); at 60 ℃; for 24h;

DOI:10.1002/cjoc.201900344

Reference yield: 90.0%

1-ethyl-4-ethynylbenzene (40307-11-7) + bis(pinacol)diborane (73183-34-3) → (E)-4,4,5,5-tetramethyl-2-(2-(4-ethylphenyl)ethenyl)-1,3,2-dioxaborolane (870717-91-2)

Guidance literature:

With ethanol; sodium methylate; at 22 ℃; for 8h; regioselective reaction;

DOI:10.1039/c8nj03708f

Reference yield: 70.0%

3-(4-ethylphenyl)propiolic acid (1181615-23-5) + bis(pinacol)diborane (73183-34-3) → (E)-4,4,5,5-tetramethyl-2-(2-(4-ethylphenyl)ethenyl)-1,3,2-dioxaborolane (870717-91-2)

Guidance literature:

With copper(l) iodide; lithium methanolate; bis[2-(diphenylphosphino)phenyl] ether; In dimethyl sulfoxide; at 50 ℃; for 16h;

DOI:10.1002/bkcs.10706

upstream raw materials:

3-(4-ethylphenyl)propiolic acid

bis(pinacol)diborane

1-ethyl-4-ethynylbenzene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

Refernces

• 1、 Bismuto, Alessandro,Cowley, Michael J.,Thomas, Stephen P.. "Zwitterion-Initiated Hydroboration of Alkynes and Styrene". supporting information. p. 2382 - 2385. Retrieved 2021/01/18.
• 2、 Ang, Nate W. J.,Buettner, Cornelia S.,Docherty, Scott,Bismuto, Alessandro,Carney, Jonathan R.,Docherty, Jamie H.,Cowley, Michael J.,Thomas, Stephen P.. "Borane-Catalysed Hydroboration of Alkynes and Alkenes". . p. 803 - 808. Retrieved 2018/02/10.