1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene

Base Information

• Chemical Name: 1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene
• CAS No.: 1187567-13-0
• Molecular Formula: C₂₆H₂₅NO₃
• Molecular Weight: 399.489
• Mol file: 1187567-13-0.mol

Synonyms:1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene

Chemical Property of 1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene

There total 1 articles about 1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1-benzyloxyphenanthrene-3-carboxylic acid (1187567-12-9) + tert-butyl alcohol (75-65-0) → 1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene (1187567-13-0)

Guidance literature:

With diphenyl phosphoryl azide; triethylamine; at 80 ℃; for 9h;

DOI:10.1016/j.tet.2009.02.065

Reference yield: 88.0%

1-(benzyloxy)-3-((tert-butyloxycarbonyl)amino)-phenanthrene (1187567-13-0) → 1-(benzyloxy)-4-bromo-3-((tert-butyloxycarbonyl)-amino)phenanthrene (1187567-14-1)

Guidance literature:

With N-Bromosuccinimide; toluene-4-sulfonic acid; In tetrahydrofuran; at -78 ℃; for 1h; regioselective reaction;

DOI:10.1016/j.tet.2009.02.065

upstream raw materials:

1-benzyloxyphenanthrene-3-carboxylic acid

tert-butyl alcohol

Downstream raw materials:

1-(benzyloxy)-4-bromo-3-((tert-butyloxycarbonyl)-amino)phenanthrene