Ursonic acid benzyl ester

Base Information

Chemical Name:Ursonic acid benzyl ester
CAS No.:869788-71-6
Molecular Formula:C37H52 O3
Molecular Weight:544.818
Hs Code.:
Mol file:869788-71-6.mol

Synonyms:3-Oxo-urs-12-en-28-oic acid phenylmethyl ester;URSONIC ACID BENZYL ESTER

Suppliers and Price of Ursonic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
URSONIC ACID BENZYL ESTER 95.00%
5MG
$ 499.61

Total 10 raw suppliers

Chemical Property of Ursonic acid benzyl ester

Chemical Property:

Melting Point:156-157 °C(Solv: ethanol (64-17-5))
Boiling Point:605.3±55.0 °C(Predicted)
PSA：43.37000
Density:1.09±0.1 g/cm3(Predicted)
LogP:8.95650

Purity/Quality:

98%Min ^*data from raw suppliers

URSONIC ACID BENZYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ursonic acid benzyl ester

There total 6 articles about Ursonic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 192211-41-9
benzyl (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,-11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

: 869788-71-6
benzyl (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,-11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

Guidance literature:: benzyl (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,-11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 - -50 ℃; for 0.25h; Inert atmosphere;

With triethylamine; In dichloromethane; at -50 - 20 ℃;

Reference yield: 92.0%

: 94482-51-6,6246-46-4
ursonic acid

: 100-39-0
benzyl bromide

: 869788-71-6
benzyl (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,-11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 12h;

Reference yield:

: 77-52-1
ursolic acid

: 869788-71-6
benzyl (1S,2R,4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,3,4,5,6,6a,6b,7,8,8a,9,10,-11,12,12a,12b,13,14b-octadecahydropicene-4a(2H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃ / dimethylformamide / 2 h / 85 °C

2: 89 percent / PCC / CH₂Cl₂ / 24 h / 0 °C

With potassium carbonate; pyridinium chlorochromate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2005.08.026