2-(Triisopropylsilyl)oxazole-5-carboxaldehyde

Base Information

Chemical Name:2-(Triisopropylsilyl)oxazole-5-carboxaldehyde
CAS No.:869542-45-0
Molecular Formula:C₁₃H₂₃NO₂Si
Molecular Weight:253.417
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80471072
Nikkaji Number:J2.251.939E
Mol file:869542-45-0.mol

Synonyms:869542-45-0;2-(Triisopropylsilyl)oxazole-5-carboxaldehyde;2-tri(propan-2-yl)silyl-1,3-oxazole-5-carbaldehyde;2-(Triisopropylsilyl)oxazole-5-carbaldehyde;SCHEMBL359178;DTXSID80471072;FBQMBIDSILZYSW-UHFFFAOYSA-N;2-triisopropylsilanyloxazole-5-carboaldehyde;2-triisopropylsilanyl-oxazole-5-carbaldehyde;2-triisopropylsilyl-oxazole-5-carboxaldehyde;2-(Triisopropylsilyl)oxazole-5-carboxaldehyde,96%;2-(Triisopropylsilyl)oxazole-5-carboxaldehyde, 96%

Suppliers and Price of 2-(Triisopropylsilyl)oxazole-5-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
2-(Triisopropylsilyl)oxazole-5-carboxaldehyde 96%
1g
$ 197.00

American Custom Chemicals Corporation
2-(TRIISOPROPYLSILYL)OXAZOLE-5-CARBOXALDEHYDE 95.00%
5G
$ 883.58

American Custom Chemicals Corporation
2-(TRIISOPROPYLSILYL)OXAZOLE-5-CARBOXALDEHYDE 95.00%
1G
$ 777.98

Total 7 raw suppliers

Chemical Property of 2-(Triisopropylsilyl)oxazole-5-carboxaldehyde

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Refractive Index:n20/D 1.5030(lit.)
Boiling Point:288.231°C at 760 mmHg
PKA:-0.97±0.10(Predicted)
Flash Point:110 °C
PSA：43.10000
Density:0.988 g/mL at 25 °C(lit.)
LogP:3.37290
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:253.149805511
Heavy Atom Count:17
Complexity:244

Purity/Quality:

98%Min ^*data from raw suppliers

2-(Triisopropylsilyl)oxazole-5-carboxaldehyde 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)[Si](C1=NC=C(O1)C=O)(C(C)C)C(C)C

Technology Process of 2-(Triisopropylsilyl)oxazole-5-carboxaldehyde

There total 1 articles about 2-(Triisopropylsilyl)oxazole-5-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 433332-27-5
2-[tris(propan-2-yl)silyl]-1,3-oxazole

: 869542-45-0
2-[tris(1-methylethyl)silyl]-1,3-oxazole-5-carbaldehyde

Guidance literature:: 2-[tris(propan-2-yl)silyl]-1,3-oxazole; With n-butyllithium; In tetrahydrofuran; at -10 ℃;

N,N-dimethyl-formamide; In tetrahydrofuran; at -10 - 20 ℃;
DOI:10.1021/jo051490m

Reference yield:

: 869542-45-0
2-[tris(1-methylethyl)silyl]-1,3-oxazole-5-carbaldehyde

: 1-(3-triisopropylsilyl-7,7-diphenyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-en-5-yl)(phenyl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: magnesium; iodine / diethyl ether / 1 h / 60 - 75 °C / Inert atmosphere

2: benzene / 20 °C / Irradiation; Inert atmosphere

With iodine; magnesium; In diethyl ether; benzene; 2: |Paterno-Buechi Cycloaddition;
DOI:10.1016/j.tet.2016.07.011

Reference yield:

: 869542-45-0
2-[tris(1-methylethyl)silyl]-1,3-oxazole-5-carbaldehyde

: 1-(3-triisopropylsilyl-7-phenyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-en-5-yl)ethanol

: 1-(3-triisopropylsilyl-7-phenyl-4,6-dioxa-2-azabicyclo[3.2.0]hept-2-en-5-yl)ethanol

Guidance literature:: Multi-step reaction with 2 steps

1: magnesium; iodine / diethyl ether / 1 h / 60 - 75 °C / Inert atmosphere

2: benzene / 20 °C / Irradiation; Inert atmosphere

With iodine; magnesium; In diethyl ether; benzene; 2: |Paterno-Buechi Cycloaddition;
DOI:10.1016/j.tet.2016.07.011