5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-

Base Information

Chemical Name:5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-
CAS No.:869470-04-2
Molecular Formula:C11H11 N O3
Molecular Weight:205.21
Hs Code.:
Mol file:869470-04-2.mol

Synonyms:5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-

Suppliers and Price of 5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-

Chemical Property:

PSA：47.89000
LogP:1.14710

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl-

There total 6 articles about 5(4H)-Oxazolone, 4-(4-methoxyphenyl)-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52771-14-9
2-acetamido-2-(4-methoxyphenyl) acetic acid

: 869470-04-2
2-methyl-4-(p-methoxyphenyl)-4H-oxazolin-5-one

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/ol052118w

Reference yield:

: 14062-18-1
ethyl p-methoxyphenylacetate

: 869470-04-2
2-methyl-4-(p-methoxyphenyl)-4H-oxazolin-5-one

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / N-bromosuccinimide; benzoyl peroxide / CCl₄ / 3 h / Heating

2: 82 percent / 15-crown-5; sodium azide / benzene / 8 h / 20 °C

3: 71 percent / p-toluenesulfonic acid monohydrate; hydrogen / Pd/C / aq. ethanol / 24 h / 20 °C / 5171.48 Torr

4: 80 percent / pyridine / CH₂Cl₂ / 8 h / 20 °C

5: 81 percent / LiOH*H₂O / ethanol / 20 h / 20 °C

6: EDCl*HCl / CH₂Cl₂ / 1 h / 0 °C

With pyridine; lithium hydroxide; N-Bromosuccinimide; sodium azide; 15-crown-5; hydrogen; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dibenzoyl peroxide; palladium on activated charcoal; In tetrachloromethane; ethanol; dichloromethane; benzene;
DOI:10.1021/ol052118w

Reference yield:

: 77629-83-5,77053-56-6
ethyl 2-bromo-2-(4-methoxyphenyl) acetate

: 869470-04-2
2-methyl-4-(p-methoxyphenyl)-4H-oxazolin-5-one

Guidance literature:: Multi-step reaction with 5 steps

1: 82 percent / 15-crown-5; sodium azide / benzene / 8 h / 20 °C

2: 71 percent / p-toluenesulfonic acid monohydrate; hydrogen / Pd/C / aq. ethanol / 24 h / 20 °C / 5171.48 Torr

3: 80 percent / pyridine / CH₂Cl₂ / 8 h / 20 °C

4: 81 percent / LiOH*H₂O / ethanol / 20 h / 20 °C

5: EDCl*HCl / CH₂Cl₂ / 1 h / 0 °C

With pyridine; lithium hydroxide; sodium azide; 15-crown-5; hydrogen; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In ethanol; dichloromethane; benzene;
DOI:10.1021/ol052118w