Technology Process of C19H32(18)FNO
There total 8 articles about C19H32(18)FNO which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Chiralpak AD-H;
In
methanol; ethanol; hexane;
Resolution of racemate;
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: aluminum (III) chloride / 1,2-dichloro-ethane / 12.33 h / 0 - 20 °C
1.2: Cooling with ice
2.1: trifluoroacetic acid; triethylsilane / 5 h / 20 °C
3.1: sodium hydroxide / 1,4-dioxane; ethanol; water / 16 h / 20 °C
4.1: thionyl chloride / dichloromethane / 5 h / 20 °C
5.1: sodium periodate / ruthenium trichloride / dichloromethane; acetonitrile; water / 2 h / 20 °C
6.1: [2.2.2]cryptande; [18F]-potassium fluoride / acetonitrile / 0.17 h / 100 °C
6.2: 0.08 h / 100 °C
7.1: samarium diiodide / tetrahydrofuran; methanol / 0.25 h / 30 °C
8.1: Chiralpak AD-H / hexane; ethanol; methanol / Resolution of racemate
With
triethylsilane; aluminum (III) chloride; sodium periodate; thionyl chloride; samarium diiodide; [18F]-potassium fluoride; [2.2.2]cryptande; trifluoroacetic acid; sodium hydroxide;
ruthenium trichloride;
In
tetrahydrofuran; 1,4-dioxane; methanol; ethanol; hexane; dichloromethane; water; 1,2-dichloro-ethane; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: thionyl chloride / dichloromethane / 5 h / 20 °C
2.1: sodium periodate / ruthenium trichloride / dichloromethane; acetonitrile; water / 2 h / 20 °C
3.1: [2.2.2]cryptande; [18F]-potassium fluoride / acetonitrile / 0.17 h / 100 °C
3.2: 0.08 h / 100 °C
4.1: samarium diiodide / tetrahydrofuran; methanol / 0.25 h / 30 °C
5.1: Chiralpak AD-H / hexane; ethanol; methanol / Resolution of racemate
With
sodium periodate; thionyl chloride; samarium diiodide; [18F]-potassium fluoride; [2.2.2]cryptande;
ruthenium trichloride;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; acetonitrile;