1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-8-methyl-

Base Information

• Chemical Name: 1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-8-methyl-
• CAS No.: 868707-84-0
• Molecular Formula: C₁₀H₁₀O₃
• Molecular Weight: 178.188
• Mol file: 868707-84-0.mol

Synonyms:8-Methyl-2,3-dihydro-1,4-benzodioxin-6-carboxaldehyde;8-Methyl-2,3-dihydrobenzo[1,4]dioxine-6-carboxaldehyde

Chemical Property of 1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-8-methyl-

Chemical Property:

• Boiling Point: 295.7±29.0 °C(Predicted)
• PSA: 35.53000
• Density: 1.217±0.06 g/cm3(Predicted)
• LogP: 1.57870

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-8-methyl-

There total 3 articles about 1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-8-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(8-methyl-2,3-dihydro-1,4-benzodioxin-6-yl)-methanol (868707-83-9) → 8-methyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (868707-84-0)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; at 0 - 20 ℃;

Reference yield: 83.0%

3-bromo-4,5-ethylenedioxybenzaldehyde (860003-88-9) + tetramethylstannane (594-27-4) → 8-methyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (868707-84-0)

Guidance literature:

With lithium chloride; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 70 ℃; for 12h;

Reference yield: 80.0%

3-bromo-4,5-ethylenedioxybenzaldehyde (860003-88-9) + Trimethylboroxine (823-96-1) → 8-methyl-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (868707-84-0)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In N,N-dimethyl-formamide; at 90 ℃; Inert atmosphere;

upstream raw materials:

(8-methyl-2,3-dihydro-1,4-benzodioxin-6-yl)-methanol

3-bromo-4,5-ethylenedioxybenzaldehyde

tetramethylstannane

Trimethylboroxine