Timodine

Base Information

• Chemical Name: Timodine
• CAS No.: 60103-17-5
• Molecular Formula: C21H30O5
• Molecular Weight: 362.46
• European Community (EC) Number: 262-053-8
• DSSTox Substance ID: DTXSID00242468
• Nikkaji Number: J298.774K
• Mol file: 60103-17-5.mol

Synonyms:Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (+-)-;Timodine

Chemical Property of Timodine

Chemical Property:

• Boiling Point: 566.4 °C at 760 mmHg
• Flash Point: 310.4 °C
• PSA: 94.83000
• Density: 1.28 g/cm³
• LogP: 1.78160
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 362.20932405
• Heavy Atom Count: 26
• Complexity: 684

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
• Isomeric SMILES: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2C(C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

Technology Process of Timodine

There total 14 articles about Timodine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.3%

9-Bromo-11,17-dihydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one → Hydrocortison (50-23-7,566-35-8,4068-92-2,4480-78-8,15437-76-0,15437-77-1,15888-35-4,60103-17-5,116907-82-5)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); sodium carbonate; HSiPh₃; In isopropyl alcohol; at 80 ℃; Green chemistry;

Reference yield:

→ Cortisol (50-23-7,566-35-8,4068-92-2,4480-78-8,15437-76-0,15437-77-1,15888-35-4,60103-17-5,116907-82-5)

Guidance literature:

s.a. Bsp. 2c, 3b, 4, 5b, 6b, 7b, 10b;

Reference yield:

C21H30O4 (152-58-9,601-05-8,3614-16-2,122405-55-4) → cortisol (50-23-7,566-35-8,4068-92-2,4480-78-8,15437-76-0,15437-77-1,15888-35-4,60103-17-5,116907-82-5) + (10R,13S,14R,17R)-14,17-Dihydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one (595-18-6)

Guidance literature:

In water; N,N-dimethyl-formamide; Cunninghamella blakesleeana;

DOI:10.1007/BF00776339

upstream raw materials:

C₂₁H₃₀O₄

Downstream raw materials:

17α.20;20.21-Bis-methylendioxy-pregnen-(4)-ol-(11β)-on-(3); 'Bismethylendioxy-hydrocortison'

4-((3R,5S,7R,10S,12S,13R)-3,7,12-Triacetoxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid methyl ester

11β,17α,21-trihydroxypregn-4-ene-3,20-dione-21-acetate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 60103-17-5 11-alpha,17-alpha,21-trihydroxypregn-4-ene-3,20-dione

Send

Send

Metric Ton KG G Pound L ML

Send

Send