14,17,21-Trihydroxypregn-4-ene-3,20-dione

Base Information

Chemical Name:14,17,21-Trihydroxypregn-4-ene-3,20-dione
CAS No.:595-18-6
Molecular Formula:C21H30 O5
Molecular Weight:362.466
Hs Code.:
European Community (EC) Number:209-858-2
NSC Number:79103
DSSTox Substance ID:DTXSID901269379
Nikkaji Number:J188.474C
ChEMBL ID:CHEMBL1970773
Mol file:595-18-6.mol

Synonyms:14,17,21-trihydroxypregn-4-ene-3,20-dione;595-18-6;NSC79103;EINECS 209-858-2;14-alpha,17-alpha,21-Trihydroxypregn-4-ene-3,20-dione;MLS002694118;NSC-79103;CHEMBL1970773;SCHEMBL10609136;DTXSID901269379;NSC 79103;NCI60_041746

Suppliers and Price of 14,17,21-Trihydroxypregn-4-ene-3,20-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 14,17,21-Trihydroxypregn-4-ene-3,20-dione

Chemical Property:

Boiling Point:559.8°Cat760mmHg
Flash Point:306.4°C
PSA：94.83000
Density:1.29g/cm³
LogP:1.92570
XLogP3:1.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:362.20932405
Heavy Atom Count:26
Complexity:699

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC(=O)C=C1CCC3C2CCC4(C3(CCC4(C(=O)CO)O)O)C
Isomeric SMILES:C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@]3(CC[C@@]4(C(=O)CO)O)O)C

Technology Process of 14,17,21-Trihydroxypregn-4-ene-3,20-dione

There total 7 articles about 14,17,21-Trihydroxypregn-4-ene-3,20-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 152-58-9
Cortexolone

: 50-23-7
HYDROCORTISONE

: 53-06-5
Cortisone

: 566-35-8
Epicortisol

: 595-18-6
14,17,21-trihydroxy-pregn-4-ene-3,20-dione

: 2899-95-8
(8S,9S,10R,11S,13S,14S,17R)-17-((R)-1,2-dihydroxyethyl)-11,17-dihydroxy-10,13-dimethyl-6,7,8, 9,10,11,12,13,14,15,16, 17-dodecahydro-1H-cyclopenta[a] phenanthrene-3 (2H)-one

Guidance literature:: In ethanol; Product distribution; culture of Cunningamella urvilaria lunata; also other cultures: C_. blakesleeana, Th_. hyalospora or Th_. hiegemella orchidis were used; different times and temperatures of their preparation before reaction;
DOI:10.1007/BF00765389