6-Bromo-1,1-(ethylenedioxo)-indane

Base Information

Chemical Name:6-Bromo-1,1-(ethylenedioxo)-indane
CAS No.:866848-94-4
Molecular Formula:C11H11 Br O2
Molecular Weight:255.11
Hs Code.:2932999099
Mol file:866848-94-4.mol

Synonyms:6-Bromo-indan-1-one 1,2-ethanediol ketal

Suppliers and Price of 6-Bromo-1,1-(ethylenedioxo)-indane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
6-Bromo-indan-1-one1,2-ethanediolketal 96%
5g
$ 3998.00

Crysdot
6'-Bromo-2',3'-dihydrospiro[[1,3]dioxolane-2,1'-indene] 95+%
1g
$ 574.00

Chemenu
6''-Bromo-2'',3''-dihydrospiro[[1,3]dioxolane-2,1''-indene] 95%
1g
$ 542.00

AOBChem
6-Bromo-indan-1-one1,2-ethanediolketal 95%
5g
$ 870.00

American Custom Chemicals Corporation
6-BROMO-1,1-(ETHYLENEDIOXO)-INDANE 95.00%
5MG
$ 502.37

Total 8 raw suppliers

Chemical Property of 6-Bromo-1,1-(ethylenedioxo)-indane

Chemical Property:

PSA：18.46000
LogP:2.59490

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-indan-1-one1,2-ethanediolketal 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-Bromo-1,1-(ethylenedioxo)-indane

There total 1 articles about 6-Bromo-1,1-(ethylenedioxo)-indane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 14548-39-1
6-bromoindan-1-one

: 107-21-1
ethylene glycol

: 866848-94-4
6‘-bromo-2‘,3‘-dihydrospiro[[1,3]dioxolane-2,1‘-indene]

Guidance literature:: With toluene-4-sulfonic acid; In benzene; at 115 ℃; for 48h; Dean-Stark; Inert atmosphere;

Reference yield: 92.0%

: 866848-94-4
6‘-bromo-2‘,3‘-dihydrospiro[[1,3]dioxolane-2,1‘-indene]

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 954238-34-7
2',3'-dihydrospiro[[1,3]dioxolane-2,1'-indene]-6'-carbaldehyde

Guidance literature:: 6‘-bromo-2‘,3‘-dihydrospiro[[1,3]dioxolane-2,1‘-indene]; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.166667h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 0.75h; Inert atmosphere;

Reference yield:

: 866848-94-4
6‘-bromo-2‘,3‘-dihydrospiro[[1,3]dioxolane-2,1‘-indene]

: C₄₁H₅₆ClFN₆O₁₀

Guidance literature:: Multi-step reaction with 13 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere

1.2: 0.75 h / -78 - 20 °C / Inert atmosphere

2.1: tetrahydrofuran / 0.5 h / 0 - 20 °C / Inert atmosphere

2.2: 1.33 h / 0 °C / Inert atmosphere

3.1: acetonitrile / 0.25 h / 20 °C / Inert atmosphere

4.1: dichloro bis(acetonitrile) palladium(II) / acetone / 0.5 h / 20 °C / Inert atmosphere

5.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere

5.2: -78 °C

6.1: [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); formic acid; triethylamine / 72 h / 20 °C / Inert atmosphere

7.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C / Inert atmosphere

8.1: 1H-imidazole / dichloromethane / 0 °C / Inert atmosphere

9.1: diphenyl phosphoryl azide / toluene / 0.08 h / 20 °C / Inert atmosphere

9.2: 20 - 70 °C / Inert atmosphere

10.1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C / Inert atmosphere

11.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / Inert atmosphere

12.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C / Inert atmosphere

13.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 1.5 h / 0 - 80 °C / Inert atmosphere; Sealed tube; Microwave irradiation

With 1H-imidazole; dichloro bis(acetonitrile) palladium(II); lithium aluminium tetrahydride; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); n-butyllithium; formic acid; diphenyl phosphoryl azide; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; hydrogen; sodium hexamethyldisilazane; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; methanol; hexane; dichloromethane; acetone; toluene; acetonitrile;